Congenital changes diagnosis of copy number in the products of conception, including aneuploidy (ie, trisomy or monosomy) and structural abnormalities.
Diagnosis of chromosomal causes of fetal death.
Determination of the risk of future pregnancy losses.
Determine the size, precise breakpoints, gene content, and any unappreciated complexity of abnormalities previously detected by other methods, such as conventional chromosomal and fluorescence in situ hybridization (FISH) tests.
To determine whether apparently balanced abnormalities identified by earlier conventional chromosome tests have cryptic imbalances, since a proportion of such rearrangements that appear balanced in a chromosome test are actually unbalanced when analyzed by higher resolution chromosome microarrays.