It is an inherited genetic neuropathy that affects the peripheral nerves, which are responsible for transmitting movement and sensation signals between the brain, spinal cord, and the rest of the body.
Charcot-Marie-Tooth disease or hereditary motor and sensory neuropathy, as it is also known, appears when alterations occur in the genes that damage the nerves of the arms, hands, legs, and feet, as well as the protective covering of the nerve, called myelin sheath.
If a direct family member suffered from Charcot-Marie-Tooth disease, you could likely develop it.
However, other factors can also contribute to its appearance, such as the presence of other neuropathies, having diabetes, or taking some medications to control chemotherapy effects.
Charcot-Marie-Tooth disease usually occurs in adolescence or early adulthood, although it can also occur during middle age.