ABC Medical Center > Glomerulosclerosis

What is Glomerulosclerosis?

21:56 - 4 May , 2021


It is a pathology that causes the scarring of kidney tissue, affecting the glomeruli, which are responsible for filtering waste from the blood.

Glomerulosclerosis affects both children and adults and is classified as:

  • Focal.
  • Segmental.

Although it is unknown what causes glomerulosclerosis, the following factors may contribute to its development:

  • Diabetes.
  • Sickle cell disease.
  • Infections.
  • Poisoning.
  • Reflux nephropathy.
  • Obesity.
  • Inherited genetic disorders.
  • Some drugs.

Signs and symptoms Glomerulosclerosis

  • Weight gain.
  • High fever.
  • Inflammation, due to fluid retention.
  • Painful urination.
  • Foamy urine from excess protein in the urine.
  • Lack of appetite.

Glomerulosclerosis risks and complications:

  • Malnutrition.
  • Infection.
  • Chronic kidney failure.
  • Nephrotic syndrome.
  • Terminal kidney disease.

Diagnosis and treatment Glomerulosclerosis

After reviewing your symptoms and medical history, your doctor will perform a physical examination to look for tissue swelling and high blood pressure.

They will also request the following tests to corroborate the diagnosis and rule out other conditions that could contribute to your symptoms:

  • Kidney biopsy.
  • Urine test.
  • Urinary microscopy.
  • Protein in the urine.
  • Kidney function tests.

The treatment to be followed will depend on the type of glomerulosclerosis you have and its severity, but the purpose is to control the symptoms and prevent kidney failure, through:

  • Antibiotics.
  • Low-fat diet.
  • Low or moderate protein diet.
  • Fluid restriction.
  • Vitamin D supplements.

In more extreme cases, the options are dialysis or a kidney transplant.

At ABC Medical Center’s Internal Medicine Department, we offer health care services with the highest quality and safety, from the prevention, diagnosis, timely treatment, and monitoring of infectious, respiratory, endocrinological, dermatological, rheumatic, nephrological, gastrointestinal, and hematological pathologies of both chronic-degenerative diseases and acute conditions, through a comprehensive and multidisciplinary model.


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  • Chávez VV, Orizaga CC, Becerra FJG, et al. Epidemiología de la enfermedad glomerular en adultos. Revisión de una base de datos. Gac Med Mex. 2014;150(5):403-408.
  • Martínez AI, Carrillo SY, Conrado HJ. Síndrome nefrótico por glomerulonefritis segmentaria focal. Informe de caso clínico. Rev Cub de Tec de la Sal. 2017;8(3):84-92.
  • Guzmán HEA, Vázquez CB, Segura CD. Mecanismos involucrados en la enfermedad renal relacionada con la obesidad. Rev Cuba Endoc. 2019;30(2):1-14.

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