Acromegaly

21:53 - 4 May , 2021

Disease

What is Acromegaly?

It is an endocrine disorder caused mainly by an excess production of growth hormone (GH) in the pituitary or hypophysis, a gland located at the base of the brain, which produces and controls various hormones, including growth hormone. It usually occurs in children, causing gigantism, and in middle-aged adults, both women and men, increasing bone volume in the face, hands, and feet. Its appearance is mainly due to the presence of a benign tumor in the pituitary. However, acromegaly can also be the result of a tumor located in another part of the body that produces the hormone or stimulates the gland to produce it. The main features of acromegaly consist of:
  • Alteration of facial features’ proportions.
  • Enlarged hands and feet.
  • Jaw and forehead growth.
  • Spaced teeth.
  • Thick lips.

Symptoms

  • Excessive and fetid sweating.
  • Burning or numbness of the hands and feet.
  • Tiredness and weakness.
  • Hypertension.
  • Joint pain.
  • Sebum.
  • Warts.
  • Deep tone of voice.
  • Decreased sexual desire.
  • Snoring.
  • Chronic fatigue.
  • Disorders in the menstrual cycle.
  • Sexual impotence in men.
  • Headaches.
  • Eyesight problems.
Possible complications of acromegaly are:
  • Hypertension.
  • Cardiomyopathies.
  • Osteoarthritis.
  • Diabetes.
  • Goiter.
  • Sleep disorders.
  • Vision problems or loss of it.
  • Tumor formation.

Diagnosis and treatment

Acromegaly is a condition that should be evaluated and treated by specialists since an excess of growth hormone in the blood affects life expectancy and quality. So your doctor, once he or she analyzes your symptoms and clinical history, will perform a physical assessment and a blood test to define your level of growth hormone, will take some X-rays to check bone thickening, and will perform an MRI to detect the presence of a tumor. The treatment to follow will depend on your case and its severity, but normalizing growth hormone levels will always be sought, either by:
  • Surgical treatment to remove the tumor.
  • Radiation of the pituitary gland.
  • Medication.
If surgery or radiation does not lower your GH level, you may require lifelong drug treatment. At ABC Medical Center’s Internal Medicine Department, we offer health care services with the highest quality and safety, from the prevention, diagnosis, timely treatment, and monitoring of infectious, respiratory, endocrinological, dermatological, rheumatic, nephrological, gastrointestinal, and hematological pathologies of both chronic-degenerative diseases and acute conditions, through a comprehensive and multidisciplinary model.

Fuentes:

  • hormone.org
  • fesemi.org
  • myhealth.ucsd.edu
  • cun.es.org
  • msdmanuals.com
  • medigraphic.com
  • González-Houdelath K. Acromegalia. Revista Médica Sinergia. 2020;5(07):1-13.
  • Boffill CS, Valdés LN, Fernández GS, et al. ¿Acromegalia doble? Informe de caso. Rev Cub de Tec de la Sal. 2011;2(1):117-123.
  • González PL; Zarate ZM. Dolor crónico en acromegalia: autoatención y apoyo familiar. Arch Med Fam. 2014;16(3):37-42.
  • Hernández-Díaz H, Orozco-Ramírez SM, de Alba-Salmerón AL, et al. Vía aérea difícil anticipada en paciente con acromegalia. Reporte de un caso. Rev Mex Anest. 2015;38(3):199-204.

						
The dissemination of the content of this material is for informational purposes only and does not replace, under any circumstance or condition, a consultation with a specialist doctor, for which the ABC Medical Center is not responsible for the different use that may be given to it. If you require more information related to the subject, we suggest you contact the specialist doctor you trust directly.