What is choroid plexus carcinoma?

It is a low-incidence oncological disease that occurs in the brain, with the probability of spreading rapidly to the cerebrospinal fluid and invading nearby tissues.

Choroid plexus carcinoma is one of the primary tumors of the central nervous system; it first develops in the brain, within the ventricles that contain cerebrospinal fluid. As the tumor becomes larger, it obstructs this fluid’s flow, causing an increase in brain pressure, an enlargement of the skull, and possible hydrocephalus.

Choroid plexus carcinoma most frequently affects children under two years old, especially boys, although it can occur in adulthood.

Although the cause of choroid plexus carcinoma is unknown, clinical studies indicate that it may be due to a genetic alteration.

Symptoms depend on where the tumor is located, as well as the child’s size, age, and health, but the following usually occur:

• Seizures.
• Headache.
• Difficulty walking
• Low energy or desire to sleep.
• Irritability.
• Nausea.
• Feeding problems
• Decreased body weight.
• Blurred or double vision.
• Vomit.
• In babies, the crown or top of the skull may protrude.

The doctor, in addition to analyzing the child’s clinical history and symptoms, will perform a physical examination and request the following tests:

• Genetic tests.
• X-rays.
• MRI.
• Computed tomography.
• Positron emission tomography.

Treatment for choroid plexus carcinoma will depend on the location of the tumor, size, age of the child, and general health, but usually includes:

• Temporary drainage.
• Surgery to try to remove the tumor in its entirety.
• Chemotherapy.
• Radiation therapy.

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