THIOPURINE METHYLTRANSFERASE TPMT ACTIVITY

Also known as: Thiopurine methyltransferase TPMT activity (TPMT3)

What you need to know about study THIOPURINE METHYLTRANSFERASE TPMT ACTIVITY

Sample type Whole blood
Delivery time 8 business days
Do I need to fast? No

What is this study and what is it for?

Screening for individuals with low thiopurine methyltransferase (TPMT) activity who are at risk of excessive myelosuppression or severe hematopoietic toxicity when taking thiopurine medications Screening for individuals with hyperactive TPMT activity who have therapeutic resistance to thiopurine medications and may develop hepatotoxicity if treated with these drugs.

What type of sample is needed?

Whole blood

Preparation / Instructions

Patients should refrain from the following medications for at least 48 hours before TPMT testing: naproxen (Aleve), ibuprofen (Advil, Motrin), ketoprofen (Orudis), furosemide (Lasix), sulfasalazine (Azulfidine), mesalamine (Asacol ), olsalazine (Dipentum), mefenamic acid (Ponstel), trimethoprim (Proloprim), methotrexate, thiazide diuretics, and benzoic acid inhibitors.

Delivery time

8 business days

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