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Precision Medicine
4 November 2025
Blastocystis hominis is a parasitic protozoan that can live in the human and animal digestive systems. It usually doesn’t cause symptoms, but it can sometimes lead to cramps, severe diarrhea, and gas, among other symptoms, which can result in serious dehydration.
Blastocystis hominis is transmitted through contact with fecal matter from infected people and animals, or by consuming contaminated water or food, causing an infectious disease known as blastocystosis.
Since there are several strains of this microorganism (which is why it is now called Blastocystis spp.), it has not been identified if only some of them are harmful or if the disease only affects people who are sensitive to it, making them more vulnerable to its effects.
In developing countries, it is estimated that more than 21% of the population has this parasite in their digestive tract.
Although many people carry this microorganism without discomfort, in some cases it can be associated with conditions such as persistent diarrhea, abdominal pain or cramps, bloating, nausea, fatigue, or changes in bowel habits.
These symptoms can be intermittent and are often confused with those of irritable bowel syndrome, which can make a diagnosis difficult.
The intensity of the discomfort can range from mild to severe and is sometimes accompanied by loss of appetite or loose stools with mucus. There may also be a feeling of incomplete bowel evacuation or an urgent need to defecate.
Although it is not clear if these symptoms are always caused by Blastocystis hominis—as it can coexist with other infections or intestinal disorders—it is important for the clinical diagnosis to be made properly.
The diagnosis of Blastocystis hominis is made through laboratory tests on stool samples, mainly by a coproparasitoscopic exam, which identifies the presence of intestinal parasites under a microscope.
However, due to the large number of organisms that may be present in the stool, it is usually recommended to analyze at least three samples collected on different days. This increases the probability of detection.

More sensitive techniques, such as a polymerase chain reaction (PCR), can be used to identify the protozoan’s genetic material and distinguish between different subtypes.
It is important to note that the presence of Blastocystis hominis in the stool does not always mean it is the cause of the symptoms. For this reason, the diagnosis must consider the patient’s clinical context, their symptoms, travel history, consumption of contaminated water or food, and the exclusion of other gastrointestinal causes.
Treatment for Blastocystis hominis is not always necessary, especially if the person is asymptomatic.
If a person has persistent or bothersome symptoms that cannot be attributed to another cause, antiparasitic medication may be prescribed. The response to treatment can vary as there are different subtypes of the parasite, some of which may be more resistant or less pathogenic.
If there is resistance or recurrence, combination therapies or a re-evaluation of the diagnosis may be considered to rule out other infections or functional disorders.
It is essential that treatment is supervised by a healthcare professional, as not all cases require medication or the use of antiparasitics, which if used incorrectly can cause side effects or lead to resistance.
It is also important to understand that symptom relief may not be immediate and requires clinical follow-up to assess the effectiveness of the treatment and the potential need to repeat studies.
Beyond providing treatment for Blastocystis hominis, it is also important to implement preventive measures that focus on improving personal hygiene and basic sanitation. Washing hands with soap and water before eating, after using the restroom, and when handling food is essential, along with drinking safe water and avoiding raw or poorly washed foods.
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Comparison of COVID-19 vaccines
Pfizer-
BioNTech
Pfizer-BioNTech
What is its effectiveness and what does it refer to?
Vaccine type: mRNA
Effectiveness: 95% after the second dose in the prevention of symptomatic COVID-19.
No Does not contain egg, latex, or preservatives.
How many doses are needed?
Two doses are needed, at least 21 days apart (or up to six weeks apart, if necessary).
Who should or shouldn’t get the vaccine?
People who should receive the vaccine are those over 16 years old.
People who should not receive the vaccine are those who have a history of anaphylactic shock (severe allergy) or who are allergic to any component of this vaccine such as polyethylene glycol (PEG) or polysorbate.
What are the possible side effects of the vaccine?
Pain where the injection was given, fatigue, headache, muscle pain, chills, joint pain, fever, nausea, malaise, and swollen lymph nodes.
How long will it take for me to be protected and what does it protect me from?
After 14 days of having the complete scheme (after the administration of the 2nd dose), the protection period is still under study. It protects us from serious COVID-19 or requiring hospitalization.
Moderna
What is its effectiveness and what does it refer to?
Vaccine type: mRNA
Effectiveness: 94.5% after the second dose in the prevention of symptomatic COVID-19.
Does not contain egg, latex, or preservatives.
How many doses are needed?
Two doses are needed, at least 28 days apart (or up to six weeks apart, if necessary).
Who should or shouldn’t get the vaccine?
People who should receive the vaccine are those over 18 years old.
People who should not receive the vaccine are those who have a history of anaphylactic shock (severe allergy) or who are allergic to any component of this vaccine.
What are the possible side effects of the vaccine?
Pain where the injection was given, fatigue, headache, muscle pain, chills, joint pain, fever, nausea, and swollen lymph nodes in the arm in which you received the injection.
How long will it take for me to be protected and what does it protect me from?
After 14 days of having the complete scheme (after the administration of the 2nd dose), the protection period is still under study. It protects us from serious COVID-19 or requiring hospitalization.
Janssen/
Johnson
& Johnson
Janssen/ Johnson & Johnson
What is its effectiveness and what does it refer to?
Vector-based vaccine.
Effectiveness: 72.0% in the prevention of symptomatic COVID-19.
85% in the prevention of severe COVID-19.
Does not contain egg, latex, or preservatives./strong>
How many doses are needed?
Only one dose in needed.
Who should or shouldn’t get the vaccine?
People who should receive the vaccine are those over 18 years old.
People who should not receive the vaccine are those who have a history of anaphylactic shock (severe allergy) or who are allergic to any component of this vaccine.
What are the possible side effects of the vaccine?
Pain where the injection was given, headache, fatigue, muscle pain, chills, fever, and nausea.
How long will it take for me to be protected and what does it protect me from?
After 28 days of having the complete scheme (the last dose applied), the protection period is still under study. It protects us from 85% serious COVID-19 or requiring hospitalization.
AstraZeneca
and
Oxford
University
AstraZeneca and Oxford University
What is its effectiveness and what does it refer to?
Adenovirus vector-based vaccine.
Effectiveness: 82% after the second dose in the prevention of symptomatic COVID-19.
How many doses are needed?
Two doses are needed, at least 56 days apart (or up to 84 days apart, if necessary).
Who should or shouldn’t get the vaccine?
People who should receive the vaccine are those over 18 years old.
People who should not receive the vaccine are those who have a history of anaphylactic shock (severe allergy) or who are allergic to any component of this vaccine.
What are the possible side effects of the vaccine?
Pain where the injection was given, fatigue, headache, myalgia, arthralgia, and fever, which were mild to moderate in intensity and disappeared within 48 hours of vaccination.
How long will it take for me to be protected and what does it protect me from?
After 14 days of having the complete scheme (after the administration of the 2nd dose), the protection period is still under study. It protects us from serious COVID-19 or requiring hospitalization.
Sputnik V
What is its effectiveness and what does it refer to?
Adenovirus vector-based vaccine.
Effectiveness: 92% after the second dose in the prevention of symptomatic COVID-19.
How many doses are needed?
Two doses are needed, at least 21 days apart (or up to six weeks apart, if necessary).
Who should or shouldn’t get the vaccine?
People who should receive the vaccine are those over 18 years old.
People who should not receive the vaccine are those who have a history of anaphylactic shock (severe allergy) or who are allergic to any component of this vaccine.
What are the possible side effects of the vaccine?
Pain where the injection was given, fatigue, headache, myalgia, arthralgia, and fever, which were mild to moderate in intensity and disappeared within 48 hours of vaccination.
How long will it take for me to be protected and what does it protect me from?
After 14 days of having the complete scheme (after the administration of the 2nd dose), the protection period is still under study. It protects us from serious COVID-19 or requiring hospitalization.
Anti-Herpes Zoster
Herpes zoster is a painful, burning rash. It usually appears on one part of the body and can last for several weeks. It can cause long-lasting severe pain and scarring. Bacterial skin infections, weakness, muscle paralysis, hearing or vision loss may occur less frequently. Herpes zoster is caused by the same virus that causes chickenpox. After you have had chickenpox, the virus that caused it remains in the body of nerve cells. Sometimes after many years, the virus becomes active again and causes herpes zoster.
Vaccination is indicated in the following cases:
Scheme type:
Rabies
Human rabies is a viral disease transmitted by the bite of an infected animal. It is characterized by acute encephalomyelitis (an aggressive response of the immune system that destroys the myelin layer of the nerves and alters its function at the level of the brain or spinal cord).
Vaccination is indicated in the following cases:
Scheme type:
There are two types.
1. Pre-exposure scheme, consists of three doses of rabies vaccine:
2. Post-exposure scheme, people not vaccinated against rabies, consists of five doses of rabies vaccine.
* If the individual continues to be at risk of exposure to the disease, revaccination should be considered.
Pneumococcal vaccines
Pneumococcal disease can cause serious infections in the lungs (pneumonia), the bloodstream (bacteremia), and the lining of the brain and spinal cord (meningitis).
Two vaccines help prevent pneumococcal disease:
Vaccination is indicated in the following cases:
Scheme type:
*One dose of Pneumococcal 13 vaccine should be given first, followed by one dose of Pneumococcal 23 vaccine, depending on your age and health.