What is Inflammatory Syndrome in Children?

It is a disorder characterized by tissue and organs inflammation, which often requires specialized hospital treatment.

Inflammatory syndrome in children is linked to a COVID-19 complication, although studies continue to be performed to determine its origin and the potential risks of suffering from it.

It usually occurs two months after being infected with coronavirus, having suffered an infectious disease, or being in contact with a family member who is sick with this virus.

Children between 5 and 11 years old are the most likely to develop this disorder, although there have also been cases of younger children, babies, and adolescents.

Without early diagnosis and proper treatment, inflammatory syndrome in children can cause serious problems in vital organs.

Signs and symptoms Inflammatory Syndrome in Children

The symptoms are usually serious, with the following warning signs:

Intense abdominal pain.
Diarrhea.
Trouble breathing.
High fever.
Swollen lips and tongue.
Swollen hands or feet.
Red eyes.
Coagulation abnormalities.
Feeling of tightness in the chest.
Cardiac disorders.

If your child has any of these symptoms, go to the emergency room immediately, since, if not treated in time, inflammatory syndrome in children can cause a fatal illness or death.

Diagnosis and treatment Inflammatory Syndrome in Children

Once the doctor analyzes the symptoms and clinical history, they will perform a physical examination and request the following tests to rule out other conditions and confirm the diagnosis, such as:

Blood and urine tests.
Cardiac ultrasound.
Abdominal ultrasound
PCR test.
X-rays.
Computed tomography.

The treatment to follow depends on the severity of the symptoms and the organs affected by the inflammation but usually includes:

Antibiotics.
Steroids.
Intravenous immunoglobulin.
Blood pressure medications.
Medications to reduce clot formation.
Ventilator.

At the Pediatric Center, we provide specialized care to children from the moment of birth until they become adults, through our pediatric care, oncology, neurology, and cardiology services at the level of the best medical centers in the world.

Related centers and departments

Pediatrics Center
Internal Medicine
High Specialty Surgery Center
Radiology and Molecular Imaging
Clinical Laboratory
Cancer Center

Fuentes:

healthychildren.org
nicklauschildrens.org
massgeneral.org
kidshealth.org
aeped.es
medline.gov
mayoclinic.org
nih.gov
medigraphic.com
Solís SAC, Ruíz CJE, Rodríguez MFI, et al. Síndrome inflamatorio multisistémico pediátrico asociado a COVID: serie de 5 casos. Rev Latin Infect Pediatr. 2022;35(4):167-175. doi:10.35366/109412.
Sánchez GJM, Castellanos MJM, Portillo GJH, et al. SARS-COV-2 asociado a síndrome inflamatorio multisistémico pediátrico: a propósito de dos casos. Enf Infec Microbiol. 2022;42(3):106-114.
Aquino-Villagómez DY, Pila-Aranda G, González-Agosto A, et al. Síndrome inflamatorio multisistémico pediátrico por SARS-CoV-2 (MIS-C). Experiencia de un Hospital de segundo nivel en Tijuana, Baja California, México. Bol Clin Hosp Infant Edo Son. 2020;37(2):78-86.

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The dissemination of the content of this material is for informational purposes only and does not replace, under any circumstance or condition, a consultation with a specialist doctor, for which the ABC Medical Center is not responsible for the different use that may be given to it. If you require more information related to the subject, we suggest you contact the specialist doctor you trust directly.

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Comparison of COVID-19 vaccines

Pfizer-
BioNTech

Pfizer-BioNTech

What is its effectiveness and what does it refer to?

Vaccine type: mRNA
Effectiveness: 95% after the second dose in the prevention of symptomatic COVID-19.

No Does not contain egg, latex, or preservatives.

How many doses are needed?
Two doses are needed, at least 21 days apart (or up to six weeks apart, if necessary).

Who should or shouldn’t get the vaccine?
People who should receive the vaccine are those over 16 years old.
People who should not receive the vaccine are those who have a history of anaphylactic shock (severe allergy) or who are allergic to any component of this vaccine such as polyethylene glycol (PEG) or polysorbate.

What are the possible side effects of the vaccine?
Pain where the injection was given, fatigue, headache, muscle pain, chills, joint pain, fever, nausea, malaise, and swollen lymph nodes.

How long will it take for me to be protected and what does it protect me from?
After 14 days of having the complete scheme (after the administration of the 2nd dose), the protection period is still under study. It protects us from serious COVID-19 or requiring hospitalization.

Moderna

What is its effectiveness and what does it refer to?

Vaccine type: mRNA
Effectiveness: 94.5% after the second dose in the prevention of symptomatic COVID-19.

Does not contain egg, latex, or preservatives.

How many doses are needed?
Two doses are needed, at least 28 days apart (or up to six weeks apart, if necessary).

Who should or shouldn’t get the vaccine?
People who should receive the vaccine are those over 18 years old.
People who should not receive the vaccine are those who have a history of anaphylactic shock (severe allergy) or who are allergic to any component of this vaccine.

What are the possible side effects of the vaccine?
Pain where the injection was given, fatigue, headache, muscle pain, chills, joint pain, fever, nausea, and swollen lymph nodes in the arm in which you received the injection.

Janssen/
Johnson
& Johnson

Janssen/ Johnson & Johnson

What is its effectiveness and what does it refer to?

Vector-based vaccine.
Effectiveness: 72.0% in the prevention of symptomatic COVID-19.
85% in the prevention of severe COVID-19.

Does not contain egg, latex, or preservatives./strong>

How many doses are needed?
Only one dose in needed.

What are the possible side effects of the vaccine?
Pain where the injection was given, headache, fatigue, muscle pain, chills, fever, and nausea.

How long will it take for me to be protected and what does it protect me from?
After 28 days of having the complete scheme (the last dose applied), the protection period is still under study. It protects us from 85% serious COVID-19 or requiring hospitalization.

AstraZeneca
and
Oxford
University

AstraZeneca and Oxford University

What is its effectiveness and what does it refer to?

Adenovirus vector-based vaccine.
Effectiveness: 82% after the second dose in the prevention of symptomatic COVID-19.

How many doses are needed?
Two doses are needed, at least 56 days apart (or up to 84 days apart, if necessary).

What are the possible side effects of the vaccine?
Pain where the injection was given, fatigue, headache, myalgia, arthralgia, and fever, which were mild to moderate in intensity and disappeared within 48 hours of vaccination.

Sputnik V

What is its effectiveness and what does it refer to?

Adenovirus vector-based vaccine.
Effectiveness: 92% after the second dose in the prevention of symptomatic COVID-19.

How many doses are needed?
Two doses are needed, at least 21 days apart (or up to six weeks apart, if necessary).

What is Inflammatory Syndrome in Children?

Signs and symptoms Inflammatory Syndrome in Children

Diagnosis and treatment Inflammatory Syndrome in Children

Related centers and departments

Fuentes:

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Specialist in Inflammatory Syndrome in Children